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Multiple Choice

Which medication is listed as first-line for pulseless ventricular tachycardia?

When a patient is in pulseless ventricular tachycardia, the priority is to restore circulation through defibrillation and high-quality CPR, and medications are used to support that effort. Epinephrine is given first because its alpha-adrenergic effects increase aortic diastolic pressure and improve coronary and cerebral perfusion during CPR, which helps achieve return of spontaneous circulation. The standard approach is to administer 1 mg IV/IO every 3–5 minutes during the arrest, coordinating with defibrillation attempts as needed. Amiodarone is added if the rhythm persists after defibrillation and epinephrine has been given, making it a subsequent antiarrhythmic rather than the first-line choice. Lidocaine is an alternative if amiodarone isn’t available, and atropine is not used for pulseless VT.

When a patient is in pulseless ventricular tachycardia, the priority is to restore circulation through defibrillation and high-quality CPR, and medications are used to support that effort. Epinephrine is given first because its alpha-adrenergic effects increase aortic diastolic pressure and improve coronary and cerebral perfusion during CPR, which helps achieve return of spontaneous circulation. The standard approach is to administer 1 mg IV/IO every 3–5 minutes during the arrest, coordinating with defibrillation attempts as needed.

Amiodarone is added if the rhythm persists after defibrillation and epinephrine has been given, making it a subsequent antiarrhythmic rather than the first-line choice. Lidocaine is an alternative if amiodarone isn’t available, and atropine is not used for pulseless VT.